Thesis
Multiscale simulations and Markov state models of peripheral membrane proteins
- Abstract:
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Peripheral membrane proteins (PMPs) interact with the cell membrane. They are important for many cell processes and are important therapeutic targets. This thesis seeks to investigate the membrane recognition and binding processes that are integral to the function of two PMP systems. Phosphatidylinositol phosphates (PIPs) are lipid signaling molecules that play key roles in many cellular processes. The PIP5K1A kinase catalyses phosphorylation of PI4P to form PIP2, which in turn ...
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Funding
Biotechnology & Biological Sciences Research Council
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:8d5a73b1-9314-4ea8-8b76-bbf0d20d9fd4
- Deposit date:
- 2020-02-28
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Terms of use
- Copyright holder:
- Amos, SBTA
- Copyright date:
- 2019
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