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Inertial cavitation at the nanoscale.

Abstract:

Our group has recently developed novel nano-sized drug carriers that spatially target a tumor and release their payload in the presence of ultrasound-induced inertial cavitation. To maximize drug release and distribution within the tumor, co-localization of the drug carrier and cavitation nuclei is necessary. We have recently demonstrated that rough-patterned silica nanoparticles can reduce inertial cavitation thresholds to clinically relevant levels, and will extravasate in tumors alongside ...

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Publisher copy:
10.1121/1.4805519

Authors


Coussios, C More by this author
Journal:
J Acoust Soc Am
Volume:
133
Issue:
5
Pages:
3315
Publication date:
2013-05-05
DOI:
EISSN:
1520-8524
ISSN:
0001-4966
URN:
uuid:8d53cab6-da5a-496f-a67b-2a9c6bb88dd5
Source identifiers:
401882
Local pid:
pubs:401882
Language:
English

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