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Journal article

Functional management of an antiviral cytotoxic T-cell response.

Abstract:

Lymphocytic choriomeningitis virus (LCMV) is known to induce strong, polyclonal cytotoxic T-lymphocyte (CTL) responses. Using a set of variant peptides derived from the major CTL epitope of LCMV, we analyzed the functional fine specificity of the LCMV-specific CTL response. During the primary response, almost all the tested peptides were recognized. In contrast, the secondary response was purged of all minor cross-reactivities and very few peptides were significantly recognized. This study is...

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Publication status:
Published

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Journal:
Journal of virology More from this journal
Volume:
71
Issue:
8
Pages:
5764-5768
Publication date:
1997-08-01
EISSN:
1098-5514
ISSN:
0022-538X
Language:
English
Keywords:
Pubs id:
pubs:469253
UUID:
uuid:8d52fd52-ceb0-4b95-af1f-dc1f8615306d
Local pid:
pubs:469253
Source identifiers:
469253
Deposit date:
2014-06-17

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