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A randomised, double-blind, controlled trial of the immunogenicity and tolerability of a meningococcal group C conjugate vaccine in young British infants.

Abstract:

A double-blind, randomised, controlled trial was conducted in 248 British infants to assess the immunogenicity and tolerability of three doses of a meningococcal group C/CRM (197) conjugate vaccine (Lederle Laboratories, USA) given at 2, 3 and 4 months. Control children received three doses of Hepatitis B vaccine (Engerix B(R); SmithKline Beecham). At 5 months of age, 100% of children receiving the conjugate vaccine had specific immunoglobulin G concentrations >2.0 microg/ml (n=116) compar...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
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Journal:
Vaccine
Volume:
19
Issue:
9-10
Pages:
1232-1238
Publication date:
2000-12-05
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
URN:
uuid:8d4e109b-d113-4720-94ab-822d1a164de2
Source identifiers:
116278
Local pid:
pubs:116278

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