Journal article icon

Journal article

Presence of the Gpr179(nob5) allele in a C3H-derived transgenic mouse.

Abstract:

PURPOSE: To identify the mutation responsible for an abnormal electroretinogram (ERG) in a transgenic mouse line (tg21) overexpressing erythropoietin (Epo). The tg21 line was generated on a mixed (C3H; C57BL/6) background and lacked the b-wave component of the ERG. This no-b-wave (nob) ERG is seen in other mouse models with depolarizing bipolar cell (DBC) dysfunction and in patients with the complete form of congenital stationary night blindness (cCSNB). We determined the basis for the nob ER...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Gassmann, M More by this author
Expand authors...
Journal:
Molecular vision
Volume:
19
Pages:
2615-2625
Publication date:
2013
EISSN:
1090-0535
ISSN:
1090-0535
URN:
uuid:8d45795c-67c7-4a03-872d-d91860bb6e2f
Source identifiers:
473968
Local pid:
pubs:473968

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP