Serotonin transporter genotype (5-HTTLPR) and electrocortical responses indicating the sensitivity to negative emotional cues.

Journal article

Growing literature indicates that emotional reactivity and regulation are strongly linked to genetic modulation of serotonergic neurotransmission. However, until now, most studies have focused on the relationship between genotypic markers, in particular the serotonin transporter-linked polymorphic region (5-HTTLPR), and neural structures using MRI. The current study aimed to bridge the gap between the relevant MRI literature on the effects of the 5-HTTLPR genotype and the research tradition f...

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Authors: Papousek, I; Reiser, E; Schulter, G; Fink, A; Holmes, E

• Publication status: Published
• Journal: Emotion (Washington, D.C.)
• Volume: 13
• Issue: 6
• Pages: 1173-1181
• Publication date: 2013-12-01
• DOI: 10.1037/a0033997
• EISSN: 1931-1516
• ISSN: 1528-3542
• Language: English
• Keywords: Middle Aged; Adult; Motivation; Electric Conductivity; Humans; Cues; Emotions; Electroencephalography; Adolescent; Genotype; Escape Reaction; Prefrontal Cortex; Serotonin Plasma Membrane Transport Proteins; Young Adult; Polymorphism, Genetic; Homozygote; Functional Laterality; Female; Magnetic Resonance Imaging; Alleles; Dopamine