Journal article
An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei.
- Abstract:
-
Trypanosoma brucei is a flagellated protozoan with a highly polarized cellular structure. TbLRTP is a trypanosomal protein containing multiple SDS22-class leucine-rich repeats and a coiled-coil domain with high similarity to a mammalian testis-specific protein of unknown function. Homologues are present in a wide range of higher eukaryotes including zebra fish, where the gene product has been implicated in polycystic kidney disease. Western blot analysis and immunofluorescence with antibodies...
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- Publication status:
- Published
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- Publisher copy:
- 10.1128/mcb.25.9.3774-3783.2005
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Bibliographic Details
- Journal:
- Molecular and cellular biology
- Volume:
- 25
- Issue:
- 9
- Pages:
- 3774-3783
- Publication date:
- 2005-05-01
- DOI:
- EISSN:
-
1098-5549
- ISSN:
-
0270-7306
- Source identifiers:
-
9376
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:9376
- UUID:
-
uuid:8d1fe736-0f2e-4bb8-8f62-517cd089efdb
- Local pid:
- pubs:9376
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2005
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