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Journal article

Analysis of HLA class II genes in Hashimoto's thyroiditis reveals differences compared to Graves' disease.

Abstract:

Graves' disease (GD) and Hashimoto's thyroiditis (HT) represent the commonest forms of autoimmune thyroid disease (AITD) each presenting with distinct clinical features. Progress has been made in determining association of HLA class II DRB1, DQB1 and DQA1 loci with GD demonstrating a predisposing effect for DR3 (DRB1(*)03-DQB1(*)02-DQA1(*)05) and a protective effect for DR7 (DRB1(*)07-DQB1(*)02-DQA1(*)02). Small data sets have hindered progress in determining HLA class II associations with HT...

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Publication status:
Published

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Publisher copy:
10.1038/gene.2008.26

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Journal:
Genes and immunity
Volume:
9
Issue:
4
Pages:
358-363
Publication date:
2008-06-05
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
URN:
uuid:8d1bb1eb-684f-4333-b9b2-960b175e9766
Source identifiers:
176373
Local pid:
pubs:176373

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