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Factors predicting successful DNA recovery from archival cervical smear samples.

Abstract:

Polymerase chain reaction (PCR)-based DNA testing of archival cervical smear slides is a useful method of retrospectively establishing the presence of the human papillomavirus (HPV) in cervical cells. A cellular DNA recovery test is performed in parallel to HPV DNA testing to ensure that sufficient cells are present and purification of sample DNA has been successfully performed. Previous studies have not comprehensively assessed DNA recovery rates in slides older than 13 years. We undertook a...

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Publication status:
Published

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Authors


Canfell, K More by this author
Snijders, P More by this author
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Journal:
Cytopathology : official journal of the British Society for Clinical Cytology
Volume:
15
Issue:
5
Pages:
276-282
Publication date:
2004-10-05
DOI:
EISSN:
1365-2303
ISSN:
0956-5507
URN:
uuid:8d162d04-d74a-4af1-99cf-b8b04252adb2
Source identifiers:
32860
Local pid:
pubs:32860

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