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Journal article

Signal transduction pathways involved in brain death-induced renal injury.

Abstract:

Kidneys derived from brain death organ donors show an inferior survival when compared to kidneys derived from living donors. Brain death is known to induce organ injury by evoking an inflammatory response in the donor. Neuronal injury triggers an inflammatory response in the brain, leading to endothelial dysfunction and the release of cytokines in the circulation. Serum levels of interleukin-6, -8, -10, and monocyte chemoattractant protein-1 (MCP-1) are increased after brain death. Binding wi...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons More from this journal
Volume:
9
Issue:
5
Pages:
989-997
Publication date:
2009-05-01
DOI:
EISSN:
1600-6143
ISSN:
1600-6135
Language:
English
Keywords:
Pubs id:
pubs:190944
UUID:
uuid:8d0bae0e-6dbe-440f-a568-dc3c76a7b734
Local pid:
pubs:190944
Source identifiers:
190944
Deposit date:
2012-12-19

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