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Journal article

Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.

Abstract:

Mosquitoes are vectors of parasitic and viral diseases of immense importance for public health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes aegypti (Aa), has enabled a comparative phylogenomic analysis of the insect immune repertoire: in Aa, the malaria vector Anopheles gambiae (Ag), and the fruit fly Drosophila melanogaster (Dm). Analysis of immune signaling pathways and response modules reveals both conservative and rapidly evolving features associate...

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Publication status:
Published

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Publisher copy:
10.1126/science.1139862

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Journal:
Science (New York, N.Y.)
Volume:
316
Issue:
5832
Pages:
1738-1743
Publication date:
2007-06-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:8cf3151f-b321-40f8-bccc-992711b53ac1
Source identifiers:
100015
Local pid:
pubs:100015

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