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Steroid effects on secretion from subsets of lactotrophs: role of folliculo-stellate cells and annexin 1.

Abstract:

Prolactin secretion is controlled by the hypothalamus, and by circulating steroids; oestrogens stimulate, but glucocorticoids inhibit prolactin release. Lactotrophs express intracellular receptors for oestrogens, but apparently not glucocorticoids. Therefore, a genomic effect of oestrogens could be direct, but that of glucocorticoids appears to be indirect. Lactotrophs are not a homogeneous cell population: some have large irregular dense-cored vesicles, others have small round vesicles, but ...

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Publisher copy:
10.1076/apab.110.1.54.910

Authors


Morris, JF More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Chapman, LP More by this author
Buckingham, JC More by this author
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Journal:
Archives of physiology and biochemistry
Volume:
110
Issue:
1-2
Pages:
54-61
Publication date:
2002-04-05
DOI:
EISSN:
1744-4160
ISSN:
1381-3455
URN:
uuid:8ce12aea-53e6-4de4-8de5-88f1865a731e
Source identifiers:
113765
Local pid:
pubs:113765

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