Journal article
First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: A meta-analysis of observational studies
- Abstract:
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BACKGROUND: Animal embryotoxicity data, and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria treatment in the first trimester except in lifesaving circumstances. We conducted a meta-analysis of prospective observational studies comparing the risk of miscarriage, stillbirth, and major congenital anomaly (primary outcomes) among first-trimester pregnancies treated with artemisinin derivatives versus quinine or no antimal...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 3.8MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pmed.1002290
Authors
- Publisher:
- Public Library of Science
- Journal:
- PLoS Medicine More from this journal
- Volume:
- 14
- Issue:
- 5
- Pages:
- e1002290
- Publication date:
- 2017-05-01
- Acceptance date:
- 2017-03-23
- DOI:
- EISSN:
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1549-1676
- ISSN:
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1549-1277
- Language:
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English
- Keywords:
- Pubs id:
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pubs:692357
- UUID:
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uuid:8cd0aca0-bfb2-4f91-9e7a-989340272734
- Local pid:
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pubs:692357
- Source identifiers:
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692357
- Deposit date:
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2017-05-10
Terms of use
- Copyright holder:
- Dellicour et al
- Copyright date:
- 2017
- Notes:
- © 2017 Dellicour et al. This is an open access article distributed under the terms of the Creative Commons Attribution License.
- Licence:
- CC Attribution (CC BY)
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