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Long-term beta-blocker treatment prevents chronic creatine kinase and lactate dehydrogenase system changes in rat hearts after myocardial infarction.

Abstract:

OBJECTIVES: We tested the hypothesis that long-term beta-blocker treatment with bisoprolol prevents creatine kinase (CK) and lactate dehydrogenase system changes that occur after chronic myocardial infarction. BACKGROUND: The mechanism of the beneficial effect of beta-blocker therapy is still unclear. METHODS: Six groups of rats were studied. Sham operated (sham) and hearts with ligated left anterior descending coronary artery (myocardial infarction) were untreated, treated early (beginning 3...

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Journal of the American College of Cardiology More from this journal
Volume:
27
Issue:
2
Pages:
487-493
Publication date:
1996-02-01
DOI:
EISSN:
1558-3597
ISSN:
0735-1097
Language:
English
Keywords:
Pubs id:
pubs:441405
UUID:
uuid:8ccb857b-f98e-4ff6-b272-23a9a07bf78b
Local pid:
pubs:441405
Source identifiers:
441405
Deposit date:
2014-02-08

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