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Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

Abstract:

BACKGROUND: The strong observational association between total homocysteine (tHcy) concentrations and risk of coronary artery disease (CAD) and the null associations in the homocysteine-lowering trials have prompted the need to identify genetic variants associated with homocysteine concentrations and risk of CAD. OBJECTIVE: We tested whether common genetic polymorphisms associated with variation in tHcy are also associated with CAD. DESIGN: We conducted a meta-analysis of genome-wide associat...

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Publication status:
Published

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Publisher copy:
10.3945/ajcn.112.044545

Authors


van Meurs, JB More by this author
Schwartz, SM More by this author
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Journal:
The American journal of clinical nutrition
Volume:
98
Issue:
3
Pages:
668-676
Publication date:
2013-09-05
DOI:
EISSN:
1938-3207
ISSN:
0002-9165
URN:
uuid:8cc7e1ed-aa82-44e8-a3c9-a988450e42f8
Source identifiers:
410930
Local pid:
pubs:410930

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