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Examination of the effect of the annealing cation on higher order structures containing guanine or isoguanine repeats.

Abstract:

Isoguanine (2-oxo-6-amino-guanine), a natural but non-standard base, exhibits unique self-association properties compared to its isomer, guanine, and results in formation of different higher order DNA structures. In this work, the higher order structures formed by oligonucleotides containing guanine repeats or isoguanine repeats after annealing in solutions containing various cations are evaluated by electrospray ionization mass spectrometry (ESI-MS) and circular dichroism (CD) spectroscopy. ...

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Publication status:
Published

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Publisher copy:
10.1002/chem.200901047

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Chemistry (Weinheim an der Bergstrasse, Germany) More from this journal
Volume:
15
Issue:
42
Pages:
11244-11255
Publication date:
2009-10-01
DOI:
EISSN:
1521-3765
ISSN:
0947-6539
Language:
English
Keywords:
Pubs id:
pubs:117667
UUID:
uuid:8cc4570d-6ff6-4c3f-9ed5-cf3034edc70c
Local pid:
pubs:117667
Source identifiers:
117667
Deposit date:
2012-12-19

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