- Abstract:
-
Plasmodium vivax is the world's most widely distributed malaria parasite and a potential cause of morbidity and mortality for approximately 2.85 billion people living mainly in Southeast Asia and Latin America. Despite this dramatic burden, very few vaccines have been assessed in humans. The clinically relevant vectors modified vaccinia virus Ankara (MVA) and the chimpanzee adenovirus ChAd63 are promising delivery systems for malaria vaccines due to their safety profiles and proven ability to...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/iai.01187-13
-
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- Journal:
- Infection and immunity
- Volume:
- 82
- Issue:
- 3
- Pages:
- 1277-1286
- Publication date:
- 2014-03-05
- DOI:
- EISSN:
-
1098-5522
- ISSN:
-
0019-9567
- URN:
-
uuid:8cb71f44-1133-44db-add8-41a61be50882
- Source identifiers:
-
445794
- Local pid:
- pubs:445794
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
Efficacy of a Plasmodium vivax malaria vaccine using ChAd63 and modified vaccinia Ankara expressing thrombospondin-related anonymous protein as assessed with transgenic Plasmodium berghei parasites.
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