Journal article icon

Journal article

Neurogenomic evidence for a shared mechanism of the antidepressant effects of exercise and chronic fluoxetine in mice.

Abstract:

Several different interventions improve depressed mood, including medication and environmental factors such as regular physical exercise. The molecular pathways underlying these effects are still not fully understood. In this study, we sought to identify shared mechanisms underlying antidepressant interventions. We studied three groups of mice: mice treated with a widely used antidepressant drug--fluoxetine, mice engaged in voluntary exercise, and mice living in an enriched environment. The h...

Expand abstract
Publication status:
Published

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0035901

Authors


Ben-David, E More by this author
Tort Piella, A More by this author
Edwards, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Expand authors...
Journal:
PloS one
Volume:
7
Issue:
4
Pages:
e35901
Publication date:
2012
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
URN:
uuid:8c98fbc1-80e2-40a2-9346-eedb6205c1ed
Source identifiers:
342678
Local pid:
pubs:342678

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP