Journal article : Review
The SNM1A DNA repair nuclease
- Abstract:
-
Unrepaired, or misrepaired, DNA damage can contribute to the pathogenesis of a number of conditions, or disease states; thus, DNA damage repair pathways, and the proteins within them, are required for the safeguarding of the genome. Human SNM1A is a 5′-to-3′ exonuclease that plays a role in multiple DNA damage repair processes. To date, most data suggest a role of SNM1A in primarily ICL repair: SNM1A deficient cells exhibit hypersensitivity to ICL-inducing agents (e.g. mitomycin C and cisplat...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- DNA Repair Journal website
- Volume:
- 95
- Article number:
- 102941
- Publication date:
- 2020-07-31
- Acceptance date:
- 2020-07-25
- DOI:
- ISSN:
-
1568-7864
- Pmid:
-
32866775
Item Description
Terms of use
- Copyright holder:
- Crown Copyright
- Copyright date:
- 2020
- Rights statement:
- Crown Copyright © 2020 Published by Elsevier B.V. This is an open access article under the CC BY license.
- Licence:
- CC Attribution (CC BY)
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