The peripheral neuronal phenotype is important in the pathogenesis of painful human tendinopathy: a systematic review.

Journal article

BACKGROUND: The pathogenesis of tendinopathy is complex and incompletely understood. Although significant advances have been made in terms of understanding the pathological changes in both the extracellular matrix and the cells involved, relatively little is known about the role of neuronal regulation in tendinopathy. The frequent mismatch between tendon pathology and pain may be explained, in part, by differences in the peripheral neuronal phenotype of patients. QUESTIONS/PURPOSES: The prima...

Expand abstract

Authors: Dean, B; Franklin, S; Carr, A

• Publication status: Published
• Journal: Clinical orthopaedics and related research
• Volume: 471
• Issue: 9
• Pages: 3036-3046
• Publication date: 2013-09-01
• DOI: 10.1007/s11999-013-3010-y
• EISSN: 1528-1132
• ISSN: 0009-921X
• Language: English
• Keywords: Pain; Rotator Cuff; Neurons; Humans; Tendinopathy; Phenotype