Cushing's syndrome caused by an occult source: difficulties in diagnosis and management.

Journal article

BACKGROUND: A 24-year-old woman presented with a 12.5 kg weight gain over 6 months (mostly abdominal), hirsutism, acne, ankle edema, polydipsia, nocturia, back pain, pigmentation, poor libido and lightened menses to our hospital in May 1986. She had been treated for the previous 2 years with furosemide and spironolactone for peripheral edema, and had stopped the combined oral contraceptive 2 months previously. She did not take tobacco, recreational drugs or alcohol. Upon physical examination...

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Authors: Grossman, AB; Kelly, P; Rockall, A; Bhattacharya, S; McNicol, A

• Publication status: Published
• Journal: Nature clinical practice. Endocrinology and metabolism
• Volume: 2
• Issue: 11
• Pages: 642-647
• Publication date: 2006-11-01
• DOI: 10.1038/ncpendmet0327
• EISSN: 1745-8374
• ISSN: 1745-8366
• Language: English
• Keywords: Female; Humans; ACTH Syndrome, Ectopic; Carcinoid Tumor; Cushing Syndrome; Long-Term Care; Appendiceal Neoplasms; Adrenalectomy; Adult