Journal article icon

Journal article

Treatment with histamine H2 antagonists in acute upper gastrointestinal hemorrhage. Implications of randomized trials.

Abstract:

Histamine H2 antagonists are widely used in treating patients with hematemesis and melena, despite the lack of reliable evidence of benefit from any of the randomized trials, considered separately. Examination of the data from all 27 available randomized trials, in which over 2500 patients were entered, suggests that treatment may reduce the rates of rebleeding, surgery, and death by about 10, 20, and 30 per cent, respectively, although these results were only marginally significant for surge...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1056/nejm198509123131104

Authors


Collins, R More by this author
Langman, M More by this author
Journal:
The New England journal of medicine
Volume:
313
Issue:
11
Pages:
660-666
Publication date:
1985-09-05
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
URN:
uuid:8c6861f6-b9f7-4ac2-9f99-4590724ecd6d
Source identifiers:
49398
Local pid:
pubs:49398

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP