- Abstract:
-
Microtubules, the dynamic, yet stiff hollow tubes built from αβ-tubulin protein heterodimers, are thought to be present only in eukaryotic cells. Here, we report a 3.6-Å helical reconstruction electron cryomicroscopy structure of four-stranded mini microtubules formed by bacterial tubulin-like Prosthecobacter dejongeii BtubAB proteins. Despite their much smaller diameter, mini microtubules share many key structural features with eukaryotic microtubules, such as an M-loop, alternating subunits...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscript
- Publisher:
- National Academy of Sciences Publisher's website
- Journal:
- Proceedings of the National Academy of Sciences Journal website
- Volume:
- 114
- Issue:
- 29
- Pages:
- E5950-E5958
- Publication date:
- 2017-07-18
- Acceptance date:
- 2017-06-01
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Pubs id:
-
pubs:710735
- URN:
-
uri:8c67b9bb-7d64-4c0b-99e1-e5cd36407657
- UUID:
-
uuid:8c67b9bb-7d64-4c0b-99e1-e5cd36407657
- Local pid:
- pubs:710735
- Paper number:
- 29
- Copyright holder:
- Deng et al.
- Copyright date:
- 2017
- Notes:
- © the author(s). Published under license by the National Academy of Sciences. This is the accepted manuscript version of the article. The final version is available online from the National Academy of Sciences at: 10.1073/pnas.1705062114
Journal article
Four-stranded mini microtubules formed by Prosthecobacter BtubAB show dynamic instability
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Boehringer Ingelheim Fonds
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