Nano-engineering of materials for nonlinear optical imaging

Journal article

Abstract:: We discuss the use of genetically modified fluorescent proteins (FPs) and a specially engineered chromophore for nonlinear optical imaging. While it is clear that FPs can be used for two-photon fluorescence (TPF) microscopy, we show that they also exhibit a large second-order nonlinear optical response, useful for second-harmonic generation (SHG) imaging. The relation between the linear and nonlinear optical properties in a small series of FPs will be discussed. We also present a new optimize...
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Role:

Author

Role:

Author

Institution:

University of Oxford

Division:

MPLS

Department:

Chemistry

Sub department:

Organic Chemistry

Role:

Author

Journal:: Proceedings of SPIE - The International Society for Optical Engineering
Volume:: 7413
Publication date:: 2009-01-01
DOI:: 10.1117/12.824517
ISSN:: 0277-786X

Language:: English
Keywords:: Two-photon fluorescence

Chromophores

Fluorescent proteins

Imaging

Second-harmonic generation
Pubs id:: pubs:331922
UUID:: uuid:8c60caa4-37ab-423c-91de-d8e4c9e9d7a3
Local pid:: pubs:331922
Source identifiers:: 331922
Deposit date:: 2012-12-19

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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