Journal article
Interplay between influenza virus and the host RNA polymerase II transcriptional machinery
- Abstract:
-
The influenza virus RNA-dependent RNA polymerase (RdRP) cleaves the 5′ end of nascent capped host RNAs and uses the capped RNA fragment to prime viral transcription in a mechanism called ‘cap snatching’. Cap snatching requires an intimate association between influenza RdRP and cellular RNA polymerase II (Pol II), which is the source of nascent capped host RNAs targeted by influenza virus. Recent structural studies have revealed how influenza RdRP binds to Pol II and how this binding promotes ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Bibliographic Details
- Publisher:
- Cell Press Publisher's website
- Journal:
- Trends in Microbiology Journal website
- Volume:
- 27
- Issue:
- 5
- Pages:
- 398-407
- Publication date:
- 2019-01-11
- Acceptance date:
- 2018-12-20
- DOI:
- ISSN:
-
0966-842X
- Source identifiers:
-
953574
Item Description
- Keywords:
- Pubs id:
-
pubs:953574
- UUID:
-
uuid:8c53a037-df6f-4e16-b28e-62b38466dafb
- Local pid:
- pubs:953574
- Deposit date:
- 2018-12-20
Terms of use
- Copyright holder:
- Walker and Fodor
- Copyright date:
- 2019
- Notes:
- Copyright © 2019 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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