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Heterogeneity of B cells reacting with T-cell factors. Evidence for matching T-cell and B-cell subsets.

Abstract:

Spleen T cells have been stimulated with Concanavalin A (Con A) under conditions which lead to the production of non-specific factor (NSF), a substance which replaces T cells for B-cell responses to certain antigens. We have examined the ability of multiple aliquots of B cells to react to the NSF derived from single T cells, and have found great heterogeneity of response. We postulate that there exist subsets of T cells which vary in either the quantity or the quality of the non-specific fact...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Immunology More from this journal
Volume:
32
Issue:
6
Pages:
915-922
Publication date:
1977-06-01
EISSN:
1365-2567
ISSN:
0019-2805
Language:
English
Keywords:
Pubs id:
pubs:8456
UUID:
uuid:8c51a7e1-5c8f-417c-bee8-c5127ffdff1f
Local pid:
pubs:8456
Source identifiers:
8456
Deposit date:
2012-12-19

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