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Regulatory T cells in atopic dermatitis: epidermal dendritic cell clusters may contribute to their local expansion.

Abstract:

BACKGROUND: Regulatory T cells (Tregs) have an essential role in tolerance and immune regulation. However, few and controversial data have been published to date on the role and number of these cells in atopic dermatitis (AD). OBJECTIVES: To investigate the number of CD4+CD25+FOXP3+ Tregs and interleukin 10-producing T regulatory type 1 (Tr1) cells in patients with AD. METHODS: Peripheral blood and skin biopsy samples from atopy patch test (APT)-positive patients with acute- and chronic-phas...

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Publication status:
Published

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Journal:
The British journal of dermatology
Volume:
160
Issue:
5
Pages:
984-993
Publication date:
2009-05-05
DOI:
EISSN:
1365-2133
ISSN:
0007-0963
URN:
uuid:8c4694be-f09a-4b93-bb59-2e89b1be07f8
Source identifiers:
246573
Local pid:
pubs:246573

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