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Basaloid squamous carcinoma of the anal canal with an adenoid cystic pattern: histologic and immunohistochemical reappraisal of an unusual variant.

Abstract:

Two cases of a distinctive variety of basaloid squamous carcinoma (BSC) of the anal canal are described. Both occurred in female patients who presented with bleeding per rectum. Histologic evaluation of the tumors showed lobules and aggregates of medium-sized basaloid cells with distinctive peripheral palisading and focal areas of central, comedo-necrosis. Accompanying dysplasia of the overlying squamous mucosa was absent. However, the microscopic pattern was dominated by the presence of eosi...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences, Biomedical Research Centre
Role:
Author
Journal:
The American journal of surgical pathology
Volume:
29
Issue:
12
Pages:
1668-1672
Publication date:
2005-12-05
DOI:
EISSN:
1532-0979
ISSN:
0147-5185
URN:
uuid:8c37346e-396a-4b2f-a145-d4f2322b22a8
Source identifiers:
121976
Local pid:
pubs:121976

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