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Comparative Genomics of Cryptococcus neoformans var. grubii Associated with Meningitis in HIV Infected and Uninfected Patients in Vietnam

Abstract:

The vast burden of cryptococcal meningitis occurs in immunosuppressed patients, driven by HIV, and is caused by Cryptococcus neoformans var. grubii. We previously reported cryptococcal meningitis in Vietnam arising atypically in HIV uninfected, apparently immunocompetent patients, caused by a single amplified fragment length polymorphism (AFLP) cluster of C. neoformans var. grubii (VNIγ). This variant was less common in HIV infected individuals; it remains unclear why this lineage is associat...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Oxford college:
Christ Church
Role:
Author
More from this funder
Name:
Royal Society
Funding agency for:
Boni, M
Baker, S
Grant:
Sir Henry Dale Fellow (098511/Z/12/Z
Sir Henry Dale Fellow (100087/Z/12/Z
More from this funder
Name:
Wellcome Trust
Funding agency for:
Day, J
Boni, M
Baker, S
Grant:
Intermediate Fellow (WT097147MA
Sir Henry Dale Fellow (098511/Z/12/Z
Sir Henry Dale Fellow (100087/Z/12/Z
Publisher:
Public Library of Science
Journal:
PLoS Neglected Tropical Diseases More from this journal
Volume:
11
Issue:
6
Pages:
e0005628
Publication date:
2017-06-14
Acceptance date:
2017-05-07
EISSN:
1935-2735
ISSN:
1935-2727
Keywords:
Pubs id:
pubs:700567
UUID:
uuid:8c34a931-afb9-44ed-9935-1be4475ce90f
Local pid:
pubs:700567
Source identifiers:
700567
Deposit date:
2017-06-15

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