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Journal article

Identification and functional characterization of cardiac troponin I as a novel disease gene in autosomal dominant dilated cardiomyopathy.

Abstract:

RATIONALE: Idiopathic dilated cardiomyopathy (DCM) is inherited in approximately one third of cases, usually as an autosomal dominant trait. More than 30 loci have been identified, several of which encode sarcomeric proteins which can also be mutated to cause hypertrophic cardiomyopathy. One contractile protein gene well known as a hypertrophic cardiomyopathy disease gene, but with no reported mutation in autosomal dominant DCM, is TNNI3 which encodes cardiac troponin I. OBJECTIVE: To test TN...

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Publication status:
Published

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Journal:
Circulation research
Volume:
105
Issue:
4
Pages:
375-382
Publication date:
2009-08-01
DOI:
EISSN:
1524-4571
ISSN:
0009-7330
Source identifiers:
104239
Language:
English
Keywords:
Pubs id:
pubs:104239
UUID:
uuid:8c319df3-6af3-4bd5-bed8-63dcc40c1352
Local pid:
pubs:104239
Deposit date:
2012-12-19

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