Journal article icon

Journal article

Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models.

Abstract:

The short-chain dehydrogenase/reductase (SDR) superfamily now has over 47 000 members, most of which are distantly related, with typically 20-30% residue identity in pairwise comparisons, making it difficult to obtain an overview of this superfamily. We have therefore developed a family classification system, based upon hidden Markov models (HMMs). To this end, we have identified 314 SDR families, encompassing about 31,900 members. In addition, about 9700 SDR forms belong to families with too...

Expand abstract
Publication status:
Published

Actions


Access Document


Journal:
FEBS journal More from this journal
Volume:
277
Issue:
10
Pages:
2375-2386
Publication date:
2010-05-01
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
Language:
English
Keywords:
Pubs id:
pubs:108364
UUID:
uuid:8c18b075-d53a-4502-86f2-ddb2efa6f3be
Local pid:
pubs:108364
Source identifiers:
108364
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP