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Heterogeneous antibody repertoire of marginal zone B cells specific for virus-like particles.

Abstract:

Marginal zone (MZ) B cells differ from follicular (FO) B cells in their functional, phenotypic and localization properties. It is still unclear whether B cells from the MZ compartment also have distinct or biased BCR specificities, recognizing only a limited number of conserved antigenic structures. To address the complexity of the immune response mounted by marginal zone B cells, we compared the antibody repertoire of murine MZ and FO B cells induced by immunization with two different virus-...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
Microbes and infection / Institut Pasteur
Volume:
9
Issue:
3
Pages:
391-399
Publication date:
2007-03-01
DOI:
EISSN:
1769-714X
ISSN:
1286-4579
Source identifiers:
469726

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