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Enhanced protein adsorption upon bulk phase separation

Abstract:

In all areas related to protein adsorption, from medicine to biotechnology to heterogeneous nucleation, the question about its dominant forces and control arises. In this study, we used ellipsometry and quartz-crystal microbalance with dissipation (QCM-D), as well as density-functional theory (DFT) to obtain insight into the mechanism behind a wetting transition of a protein solution. We established that using multivalent ions in a net negatively charged globular protein solution (BSA) can ei...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Nature Reaserch
Journal:
Scientific Reports More from this journal
Volume:
10
Article number:
10349
Publication date:
2020-06-25
Acceptance date:
2020-05-11
DOI:
EISSN:
2045-2322
Pmid:
32587383
Language:
English
Keywords:
Pubs id:
1115930
Local pid:
pubs:1115930
Deposit date:
2020-07-27

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