Journal article
Genomic characterization of recrudescent plasmodium malariae after treatment with artemether/lumefantrine
- Abstract:
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Plasmodium malariae is the only human malaria parasite species with a 72-hour intraerythrocytic cycle and the ability to persist in the host for life. We present a case of a P. malariae infection with clinical recrudescence after directly observed administration of artemether/lumefantrine. By using whole-genome sequencing, we show that the initial infection was polyclonal and the recrudescent isolate was a single clone present at low density in the initial infection. Haplotypic analysis of th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 3.4MB)
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- Publisher copy:
- 10.3201/eid2308.161582
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Authors
Funding
Bibliographic Details
- Publisher:
- Centers for Disease Control and Prevention Publisher's website
- Journal:
- Emerging Infectious Diseases Journal website
- Volume:
- 23
- Issue:
- 8
- Pages:
- 1300-1307
- Publication date:
- 2017-08-01
- DOI:
- EISSN:
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1080-6059
- ISSN:
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1080-6040
- Source identifiers:
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710332
Item Description
Terms of use
- Copyright holder:
- Centers for Disease Control and Prevention
- Copyright date:
- 2017
- Notes:
- © 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.
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