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Influenza H2 haemagglutinin activates B cells via a MyD88-dependent pathway.

Abstract:

Influenza viruses are serious respiratory pathogens, responsible for half a million deaths each year. The viral surface haemagglutinin (HA) protein has been shown to be an important determinant of viral pathogenicity. HA is the virion attachment and fusion protein, and the major target for neutralizing antibodies; however, it is also involved in triggering innate responses that may have an important impact on the disease course. We have examined the role of the toll-like receptor (TLR) family...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200535331

Authors


Journal:
European journal of immunology More from this journal
Volume:
36
Issue:
1
Pages:
95-106
Publication date:
2006-01-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Language:
English
Keywords:
Pubs id:
pubs:33322
UUID:
uuid:8bfe2487-a618-4ff8-998f-3775b231bb74
Local pid:
pubs:33322
Source identifiers:
33322
Deposit date:
2012-12-19

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