Time trends in childhood cancer: Britain 1966-2005

Thesis

Increasing time trends in the recorded incidence of childhood cancer have been reported in many different settings. The extent to which these trends reflect real changes in incidence, rather than improvements in methods for diagnosis and registration, is controversial. Using data from the National Registry of Childhood Tumours (NRCT), this thesis investigates time trends in cancer diagnosed under age 15 in residents of Britain during 1966-2005 (54650 cases), and considers potential sources...

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Authors: Kroll, M

• Publication date: 2009
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: Oxford University, UK
• Language: English
• Keywords: childhood cancer; under-diagnosis; Poisson regression; deprivation; UK; CNS tumours; standardised rates; leukaemia; imaging; acute lymphoblastic leukaemia; epidemiology; affluence; fatal infection hypothesis; incidence; capture-recapture; completeness; time trend; paediatric; cancer registration; socioeconomic status; hospital episode statistics; temporal trends; international classification of childhood cancers; delayed diagnosis; Britain; National Registry of Childhood Tumours; childhood; flow method; artefact; cancer diagnosis; geographical variation; birth cohort; cancer
• Subjects: Childhood cancer; Medical Sciences; Tumours; History of technology; Oncology; Public Health; Cancer diagnosis; Social disadvantage; Children and youth; Social Inequality; Paediatrics; History of medicine; Cancer incidence; Statistics (social sciences); Epidemiology; Social status; Cancer registration