Journal article
Mechanochemical approaches towards the in situ confinement of 5-FU anti-cancer drug within MIL-100 (Fe) metal–organic framework
- Abstract:
- We elucidate two annealing assisted mechanochemical methods to achieve one-pot encapsulation of anti-cancer drug 5-fluorouracil (5-FU) in the iron-based MIL-100 metal–organic framework (MOF). We compare the structural and physicochemical properties of drug@MIL-100 systems derived from in situ manual and vortex grinding, where the former technique exhibits a slower drug release due to stronger guest–host interactions.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- CrystEngComm Journal website
- Volume:
- 22
- Issue:
- 27
- Pages:
- 4526-4530
- Publication date:
- 2020-06-29
- Acceptance date:
- 2020-06-29
- DOI:
- EISSN:
-
1466-8033
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1116200
- Local pid:
- pubs:1116200
- Deposit date:
- 2020-07-03
Terms of use
- Copyright holder:
- Royal Society of Chemistry
- Copyright date:
- 2020
- Rights statement:
- © The Royal Society of Chemistry 2020. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence
- Licence:
- CC Attribution (CC BY)
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