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Journal article

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa.

Abstract:

Background

In 2012, the World Health Organization recommended blocking the transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target dose 0.25 mg base/kg body weight), without testing for glucose-6-phosphate dehydrogenase deficiency (G6PDd), when treating patients with uncomplicated falciparum malaria. We sought to develop an age-based SLDPQ regimen that would be suitable for sub-Saharan Africa.

Methods

Using data on the anti-infectivity...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/s12916-017-0990-6

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Tropical Medicine
Role:
Author
More from this funder
Name:
Wellcome Trust
Grant:
203077
More from this funder
Name:
National Institutes of Health
Publisher:
BioMed Central
Journal:
BMC Medicine More from this journal
Volume:
16
Issue:
1
Pages:
11
Publication date:
2018-01-01
Acceptance date:
2017-12-12
DOI:
EISSN:
1741-7015
Language:
English
Keywords:
Pubs id:
pubs:821205
UUID:
uuid:8bc0fef9-556d-436c-9fba-f0680818c39c
Local pid:
pubs:821205
Source identifiers:
821205
Deposit date:
2018-01-26

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