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Cytokine gene polymorphisms in autoimmune thyroid disease.

Abstract:

Susceptibility to the autoimmune thyroid diseases, Graves' disease (GD) and autoimmune hypothyroidism (AIH), depends on a complex interaction between environmental and genetic factors. The human leukocyte antigen and cytotoxic T lymphocyte-associated-4 regions appear to influence susceptibility to disease, but the effect is not major, and the other genes remain unknown. Cytokines are crucial in the regulation of immune and inflammatory responses and therefore are potential candidate genes for...

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Publication status:
Published

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Publisher copy:
10.1210/jc.85.5.1984

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Journal:
Journal of clinical endocrinology and metabolism
Volume:
85
Issue:
5
Pages:
1984-1988
Publication date:
2000-05-01
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Source identifiers:
18487

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