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Parkinsonian impairment correlates with spatially extensive subthalamic oscillatory synchronization.

Abstract:

The local strength of pathological synchronization in the region of the subthalamic nucleus (STN) is emerging as a possible factor in the motor impairment of Parkinson's Disease (PD). In particular, correlations have been repeatedly demonstrated between treatment-induced suppressions of local oscillatory activity in the beta frequency band and improvements in motor performance. However, a mechanistic role for beta activity is brought into question by the difficulty in showing a correlation be...

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Publication status:
Published

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Authors


Pogosyan, A More by this author
Yoshida, F More by this author
Martinez-Torres, I More by this author
Foltynie, T More by this author
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Journal:
Neuroscience
Volume:
171
Issue:
1
Pages:
245-257
Publication date:
2010-11-05
DOI:
EISSN:
1873-7544
ISSN:
0306-4522
URN:
uuid:8bb0767e-a1ff-4929-97a2-43cd4d9845ca
Source identifiers:
120783
Local pid:
pubs:120783

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