Journal article
Determining sample size in a personalized randomized controlled (PRACTical) trial
- Abstract:
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In clinical settings with no commonly accepted standard-of-care, multiple treatment regimens are potentially useful, but some treatments may not be appropriate for some patients. A personalized randomized controlled trial (PRACTical) design has been proposed for this setting. For a network of treatments, each patient is randomized only among treatments which are appropriate for them. The aim is to produce treatment rankings that can inform clinical decisions about treatment choices for indivi...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.4MB, Terms of use)
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(Preview, Supplementary materials, pdf, 325.9KB, Terms of use)
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- Publisher copy:
- 10.1002/sim.10168
Authors
Bibliographic Details
- Publisher:
- Wiley
- Journal:
- Statistics in Medicine More from this journal
- Volume:
- 43
- Issue:
- 21
- Pages:
- 4098-4112
- Publication date:
- 2024-07-09
- Acceptance date:
- 2024-06-21
- DOI:
- EISSN:
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1097-0258
- ISSN:
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0277-6715
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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2011453
- Local pid:
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pubs:2011453
- Deposit date:
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2024-07-02
Terms of use
- Copyright holder:
- Turner et al.
- Copyright date:
- 2024
- Rights statement:
- © 2024 The Author(s). Statistics in Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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