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ELISA determination of IgG antibodies to pneumococcal capsular polysaccharides in a group of children.

Abstract:
An enzyme-linked immunosorbent assay (ELISA) was developed to measure specific IgG antibody levels to pneumococcal polysaccharide antigens in 300 children attending various hospital departments. By expressing the results as a specific binding index (SBI) of given high and low controls, good reproducibility was obtained. Serum levels of the antibodies were found to fall rapidly during the 1st year of life, plateau during the 2nd and then rise steadily, reaching adult levels by the 7th year.

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Authors


Windebank, KP More by this author
Chapel, HM More by this author
Journal:
Journal of immunological methods
Volume:
104
Issue:
1-2
Pages:
143-148
Publication date:
1987-11-05
DOI:
EISSN:
1872-7905
ISSN:
0022-1759
URN:
uuid:8b8e42d3-5f06-4236-a89f-8ffab1b80ddb
Source identifiers:
94174
Local pid:
pubs:94174

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