Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice.

Garner, B; Priestman, DA; Stocker, R; Harvey, DJ; Butters, TD; Platt, FM

Abstract:

The apolipoprotein E gene knockout (apoE-/-) mouse develops atherosclerosis that shares many features of human atherosclerosis. Increased levels of glycosphingolipid (GSL) have been reported in human atherosclerotic lesions; however, GSL levels have not been studied in the apoE-/- mouse. Here we used HPLC methods to analyze serum and aortic GSL levels in apoE-/- and C57BL/6J control mice. The concentrations of glucosyl ceramide (GlcCer), lactosyl ceramide (LacCer), GalNAcbeta1-4Galbeta1-4Glc-...

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APA Style

Garner, B., Priestman, D. A., Stocker, R., Harvey, D. J., Butters, T. D., & Platt, F. M. (2002). Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice. Journal of Lipid Research, 43(2), 205–214.

MLA Style

Garner, B., et al. “Increased Glycosphingolipid Levels in Serum and Aortae of Apolipoprotein E Gene Knockout Mice.” Journal of Lipid Research, vol. 43, no. 2, 2002, pp. 205–14.

Chicago Style

Garner, B, DA Priestman, R Stocker, DJ Harvey, TD Butters, and FM Platt. 2002. “Increased Glycosphingolipid Levels in Serum and Aortae of Apolipoprotein E Gene Knockout Mice.” Journal of Lipid Research 43 (2): 205–14.
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