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Journal article

Stochasticity and the molecular mechanisms of induced pluripotency

Abstract:

The generation of induced pluripotent stem cells from adult somatic cells by ectopic expression of key transcription factors holds significant medical promise. However, current techniques for inducing pluripotency rely on viral infection and are therefore not, at present, viable within a clinical setting. Thus, there is now a need to better understand the molecular basis of stem cell pluripotency and lineage specification in order to investigate alternative methods to induce pluripotency for ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0003086

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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
Publisher:
Public Library of Science
Journal:
PLoS ONE More from this journal
Publication date:
2008-08-28
Acceptance date:
2008-08-07
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
UUID:
uuid:8b8224aa-e968-4eef-86eb-2dc003a6f85a
Local pid:
pubs:357199
Source identifiers:
357199
Deposit date:
2013-11-16

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