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Journal article

Cross-linking of porcine acellular dermal matrices negatively affects induced neovessel formation using platelet-rich plasma in a rat model of hernia repair.

Abstract:

The degree of cross-linking within acellular dermal matrices (ADM) seems to correlate to neovascularization when used in ventral hernia repair (VHR). Platelet-rich plasma (PRP) enhances wound healing through several mechanisms including neovascularization, but research regarding its effect on soft tissue healing in VHR is lacking. We sought to study the effect of cross-linking on PRP-induced neovascularization in a rodent model of bridging VHR. We hypothesized that ADM cross-linking would neg...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/wrr.12508

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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Name:
Houston Methodist Research Institute
Publisher:
Wiley
Journal:
Wound Repair and Regeneration More from this journal
Volume:
25
Issue:
1
Pages:
98-108
Publication date:
2017-01-01
Acceptance date:
2016-12-15
DOI:
EISSN:
1524-475X
ISSN:
1067-1927
Language:
English
Keywords:
Pubs id:
pubs:672353
UUID:
uuid:8b7ce93a-5adc-4c0c-9e6a-256569b87f17
Local pid:
pubs:672353
Source identifiers:
672353
Deposit date:
2017-05-03

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