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Modelling Delta-Notch perturbations during zebrafish somitogenesis

Abstract:

The discovery over the last 15 years of molecular clocks and gradients in the pre-somitic mesoderm of numerous vertebrate species has added significant weight to Cooke and Zeeman's 'clock and wavefront' model of somitogenesis, in which a travelling wavefront determines the spatial position of somite formation and the somitogenesis clock controls periodicity (Cooke and Zeeman, 1976). However, recent high-throughput measurements of spatiotemporal patterns of gene expression in different zebrafi...

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Publisher copy:
10.1016/j.ydbio.2012.10.014
Journal:
Developmental Biology More from this journal
Volume:
373
Issue:
2
Pages:
407-421
Publication date:
2013-01-15
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
Language:
English
Keywords:
Pubs id:
pubs:377352
UUID:
uuid:8b6e96bb-a9e8-4129-979e-1ac4a0789dee
Local pid:
pubs:377352
Source identifiers:
377352
Deposit date:
2013-11-17

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