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RIDL: A tool to investigate radiation-induced density loss

Abstract:

An automated tool, RIDL (Radiation-Induced Density Loss), has been developed that enables user-independent detection and quantification of radiation-induced site-specific changes to macromolecular structures as a function of absorbed dose. RIDL has been designed to extract suitable peratom descriptors of radiation damage, based on changes detectable in Fobs, n– Fobs, 1Fourier difference maps between successive dose data sets. Subjective bias, which frequently plagues the interpretation of tru...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
Brasenose College
Role:
Author
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Name:
Engineering and Physical Sciences Research Council
Grant:
EP/G03706X/1
Publisher:
International Union of Crystallography
Journal:
Journal of Applied Crystallography More from this journal
Volume:
51
Issue:
3
Pages:
952-962
Publication date:
2018-05-18
Acceptance date:
2018-04-03
DOI:
ISSN:
1600-5767
Keywords:
Pubs id:
pubs:858736
UUID:
uuid:8b5abb6c-a572-49f1-89a9-15d89a64251e
Local pid:
pubs:858736
Source identifiers:
858736
Deposit date:
2018-10-25

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