Conference item
Direct Pharmacokinetic Parameter Estimation using Weighted Least Squares
- Abstract:
-
Conventional dynamic PET studies estimate pharmacokinetic parameters using a two-step procedure of first reconstructing the spatial activity volume for each temporal frame independently before applying a pharmacokinetic model to the resulting spatio-temporal activity distribution. This indirect procedure leads to low SNR due to using only a subset of the temporal data when reconstructing each image. Our work concentrates on the estimation of parameters directly from the (raw or pre-corrected)...
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- Publication status:
- Published
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Bibliographic Details
- Host title:
- MEDICAL IMAGING 2010: PHYSICS OF MEDICAL IMAGING
- Volume:
- 7622
- Issue:
- PART 2
- Publication date:
- 2010-01-01
- DOI:
- ISSN:
-
0277-786X
- ISBN:
- 9780819480231
Item Description
- Keywords:
- Pubs id:
-
pubs:110233
- UUID:
-
uuid:8b4f5031-a9eb-4d47-b111-e0a313aa982a
- Local pid:
- pubs:110233
- Source identifiers:
-
110233
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2010
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