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The distribution of CD45R, CD29 and CD45RO (UCHL1) antigens in mature CD4 positive T-cell leukaemias.

Abstract:

We have studied the expression of antigens characterizing functional T-cell subsets in 32 CD4+ mature T-cell leukaemias. In this analysis we used two monoclonal antibodies (McAb) of the CD45R group (2H4 and GRT22) which have been shown to identify the 'native/virgin' T-cell population that functions as 'suppressor-inducer' cells in vitro, and two McAb, CD29 (4B4) and CD45RO (UCHL1), which characterize non-identical 'memory' cells that proliferate in response to soluble recall antigens and pro...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
British journal of haematology More from this journal
Volume:
74
Issue:
4
Pages:
439-444
Publication date:
1990-04-01
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
Language:
English
Keywords:
Pubs id:
pubs:35139
UUID:
uuid:8b3db009-90ba-4e36-8948-0501d2dfab72
Local pid:
pubs:35139
Source identifiers:
35139
Deposit date:
2012-12-20

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