The distribution of CD45R, CD29 and CD45RO (UCHL1) antigens in mature CD4 positive T-cell leukaemias.

Journal article

We have studied the expression of antigens characterizing functional T-cell subsets in 32 CD4+ mature T-cell leukaemias. In this analysis we used two monoclonal antibodies (McAb) of the CD45R group (2H4 and GRT22) which have been shown to identify the 'native/virgin' T-cell population that functions as 'suppressor-inducer' cells in vitro, and two McAb, CD29 (4B4) and CD45RO (UCHL1), which characterize non-identical 'memory' cells that proliferate in response to soluble recall antigens and pro...

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Authors: Worner, I; Matutes, E; Beverley, P; Catovsky, D

• Journal: British journal of haematology
• Volume: 74
• Issue: 4
• Pages: 439-444
• Publication date: 1990-04-01
• DOI: 10.1111/j.1365-2141.1990.tb06332.x
• EISSN: 1365-2141
• ISSN: 0007-1048
• Language: English
• Keywords: Flow Cytometry; Antigens, CD; Leukemia, Lymphoid; Cell Separation; Humans; T-Lymphocytes; Leukemia, Prolymphocytic; Leukemia-Lymphoma, Adult T-Cell; Antigens, Neoplasm; Sezary Syndrome; Leukemia; Antigens, CD4