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Safety, tolerability, and efficacy of cyclosporine microemulsion in heart transplant recipients: a randomized, multicenter, double-blind comparison with the oil-based formulation of cyclosporine--results at 24 months after transplantation.

Abstract:

BACKGROUND: The widespread use of cyclosporine has improved the survival of cardiac transplant patients as a result of reduced morbidity and mortality from rejection and infection. The original oil-based form of cyclosporine demonstrated unpredictable absorption resulting in an increased frequency of acute and chronic rejection in patients with poor bioavailability. The primary end. points of the present, prospective, randomized multicenter, double-blind trial were to compare the efficacy of ...

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Authors


Carrier, M More by this author
Mancini, DM More by this author
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Journal:
Transplantation
Volume:
71
Issue:
1
Pages:
70-78
Publication date:
2001-01-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:8b121174-6ec6-4cf6-a7b2-49eab2170844
Source identifiers:
223069
Local pid:
pubs:223069

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